Therefore this dysregulation of the immune system attack healthy cells. Autoimmune diseases can affect many different types of body tissue. In the absence of curative therapy, treatment for autoimmune diseases focuses only on relieving symptoms.
There is a growing body of scientific evidence to suggest that the gut microbiome plays an important role in modulating mechanisms of response and resistance to cancer immunotherapies. In January , Enterome has announced a collaborative research agreement with Janssen Biotech, Inc. In January , Enterome has announced a strategic drug discovery collaboration with Takeda Pharmaceutical, to research and develop potential new therapeutics directed at microbiome targets thought to play crucial roles in gastrointestinal disorders, including inflammatory bowel diseases e.
In October , Enterome has entered into a global licensing, co-development and co-promotion agreement with Takeda Pharmaceutical. Pierre Belichard has served as our Chief Executive Officer since and as a member of our board of directors since Previously, Dr. From to , Dr. From to , he served as head of European commercial operations at Ethypharm S. Belichard holds a Pharm. Our board of directors believes that Dr. Simon Baeriswyl has served as our Chief Operating Officer since Baeriswyl worked at Sanofi S.
Baeriswyl served as a Management Consultant with the healthcare practice of the Boston Consulting Group. Baeriswyl managed a family-owned medical practice. Baeriswyl holds a Ph. Christophe Bonny has served as our Chief Scientific Officer since Before joining us, Dr. In , Dr.
Novel Molecular Targets for Drug Development in Non-GIST Sarcomas
Bonny received the Pfizer Research Prize. Bonny holds a Ph. Bouttier joined Fovea Pharmaceuticals SA at its inception in as a business development associate and held a position in the licensing and contractual operations through the sale to Sanofi S.
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From to , Ms. Bouttier was a business development associate at UroGene, S. Rodolphe Clerval has served as our Chief Business Officer since Before joining us, from to , Mr. From to , Mr. Clerval was an equity analyst for the brokerage firm, Natixis Bleichroeder Inc. Clerval holds an M. Christelle Dumoussaud has served as our Chief Financial Officer since In , Ms. From to December , Dr. Fagerberg was Medical Director at TopoTarget from to Fagerberg held various positions of increasing responsibility at Roche from to in medical and clinical operations after ten years of oncology practice and academic translational immune-oncology research at Karolinska Hospital.
Fagerberg holds an M. She developed robust expertise for developing innovative healthcare products from Phase 1 to phase 3 studies with an excellent product knowledge concerning US and EU regulations. Earlier, she took over the position of VP, regulatory affairs at TxCell in cell therapy. Prior to that, Catherine served for several years as head of regulatory affairs at Transgene developing immunotherapy products based on recombinant viruses. She started her career at Ipsen and Sanofi Pasteur in clinical research. Catherine is Pharm D and holds a master degree in toxicology.
Georges Gemayel has served as chairman of our board of directors since From June to November , Dr. Gemayel held progressively senior roles at Hoffmann La-Roche Inc. Working across the boundaries and integration of skills from traditional scientific disciplines will provide an optimal level of cross-training between basic, translational and clinical science. The aim is to provide the trainees with advanced skills to pursue their independent careers as basic science researchers and physician-scientists with an emphasis on GI disorders. The trainees can choose to pursue their training in one of these areas of Gastroenterology:.
Molecular Training in Gastroenterology krystle2 T Our board of directors believes that Ms.
Roger Garceau has served as a member of our board of directors since Garceau is a board certified pediatrician with approximately 30 years of experience in pharmaceutical development, global regulatory and medical affairs. Garceau worked at NPS Pharmaceuticals. Garceau currently serves on the board of directors of EnteraBio Ltd. Garceau holds a B. Before joining Lundbeckfonden Ventures, Dr. Since , Dr. Andrea Pederzolli has served as a member of our board of directors since March and has served as representative of Principia SGR SpA, the legal entity that holds this board seat, since June Since , Mr.
Pederzolli started his career as an electronic engineer designing satellite communication networks and later moved to the financial sector working in London at the Industrial Bank of Japan as an Associate, Structuring and Customer Risk Management from to , Barclays Capital as Medium Term Notes Associate Director from to , and Merrill Lynch as Vice President Corporate Risk Management from to In , Mr.
Pederzolli founded MangustaRisk. Pederzolli holds an M. Mary Thistle has served as a member of our board of directors since Since January , Ms.
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Thistle served in several roles at Cubist Pharmaceuticals Inc. Prior to this, from to , Ms. Thistle held leadership positions at ViaCell, Inc. Thistle is currently a member of the board of directors for Homology Medicines, Inc.
Thistle is also on the board of directors for Coccon Biotech, Inc. Thistle began her career in finance as a certified public accountant working with both private and public companies. She received her B. This technology enables the identification of biomarkers and of bacteria of interest associated with the development of diseases.
We have entered into a global strategic alliance with Takeda Pharmaceutical Company Limited, or Takeda, for the co-development and co-commercialization of EB In collaboration with Takeda, we have designed a Phase 2a clinical trial of EB, and we expect to commence enrollment of this trial in EB is a therapeutic program for the discovery of new drug candidates for the treatment of Inflammatory Bowel Diseases. Enterome and Takeda Pharmaceutical jointly collaborate for the development of new drug candidates for the treatment of severe GI disorders.
EO EO is an innovative, off-the-shelf immunotherapy comprised of three onco-mimics, which are highly homologous to solid tumor antigens. EO mimics three key tumor antigens that are highly expressed by brain tumors, including GBM, as well as other tumor types. Our second product candidate, EO, is an innovative, off-the-shelf immunotherapy comprised of three microbiome-derived antigens, which are highly homologous to solid tumor antigens.watch
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We refer to these microbiome- derived antigens, which are bacterial short peptides that have high amino acid sequence homology with known human tumor antigens and neoantigens, as onco-mimics. EO mimics three key tumor antigens that are highly expressed by brain tumors, including glioblastoma multiforme, or GBM, as well as other tumor types. Furthermore, we have demonstrated that this response is synergistic when combined with checkpoint inhibitors both in vitro and in vivo.
Beyond EO, we have filed a patent application covering novel onco-mimics to date, targeting 78 human tumor antigens highly expressed in 20 broad tumor types, and we plan to continue to explore other combinations of onco-mimic candidates for the treatment of various forms of cancer. EO is a therapeutic program for the discovery of new drug candidates for the treatment of cancer. Enterome and Bristol-Myers Squibb jointly collaborate for the discovery of novel biomarkers.
Seventure is a subsidiary of Natixis. Lundbeckfonden Ventures is a life science venture fund established in and wholly owned by the Lundbeck Foundation. Investments are made within lifescience, focusing on pharmaceuticals and biopharmaceuticals, medtech, diagnostics and healthcare service companies.
Omnes Capital is a major player in private equity, with a commitment to financing SMEs. For more information, please visit: www. Health for Life Capital supports innovative high-growth entrepreneurial ventures.
Geographically, its focus is primarily in Europe, but also extends to North America and Asia. Investments will be made in the areas of healthcare, life sciences, biotechnology, medical technologies, pharmaceuticals, nutrition and in the emerging fields of microbiome and connected health.